androidsixteen
@androidsixteen.eth
It’s ironic that we’re simultaneously acknowledging the downsides of plastics and promoting GLP-1 meds It’s the hubris of a materially advanced society — we can’t fathom how engineering our materials and our bodies could be bad for us Though the negatives of GLPs will likely be discovered sooner (spoiler alert: muscle loss)
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DV
@degenveteran.eth
Question about the muscle loss comment, have you read something recently? I haven't looked into all this so I am not up to date. Educational guess I'd say it's in relationship to losing weight doing nothing as opposed to previously people would actually work out etc...
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androidsixteen
@androidsixteen.eth
https://www.sciencedirect.com/science/article/pii/S2452302X24002869 “While these findings are promising for CV patients, a side-effect of GLP-1RAs use is the loss of skeletal muscle (lean BW) mass.” “Overall, these data show that semaglutide has an effect on the cardiomyocyte resulting in reduced cardiomyocyte size and cardiac mass in lean and obese mice”
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DV
@degenveteran.eth
Ahhh interesting, so from a CV study. 🙏
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Trejo
@trej
Research aside, my fitness company has been receiving an influx of requests for our trainers to aid them while on GLP-1. Anecdotally, muscle loss seems to happen before the fat loss. I haven’t seen a direct causative study on this but it seems it’s more than just losing muscle from inactivity. There seems to be a correlation between the compound and direct muscle loss.
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