androidsixteen
@androidsixteen.eth
Itās ironic that weāre simultaneously acknowledging the downsides of plastics and promoting GLP-1 meds Itās the hubris of a materially advanced society ā we canāt fathom how engineering our materials and our bodies could be bad for us Though the negatives of GLPs will likely be discovered sooner (spoiler alert: muscle loss)
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DV
@degenveteran.eth
Question about the muscle loss comment, have you read something recently? I haven't looked into all this so I am not up to date. Educational guess I'd say it's in relationship to losing weight doing nothing as opposed to previously people would actually work out etc...
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androidsixteen
@androidsixteen.eth
https://www.sciencedirect.com/science/article/pii/S2452302X24002869 āWhile these findings are promising for CV patients, a side-effect of GLP-1RAs use is the loss of skeletal muscle (lean BW) mass.ā āOverall, these data show that semaglutide has an effect on the cardiomyocyte resulting in reduced cardiomyocyte size and cardiac mass in lean and obese miceā
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DV
@degenveteran.eth
Ahhh interesting, so from a CV study. š
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androidsixteen
@androidsixteen.eth
I think there is more research out there if you dig I also have a thesis thatās more in line with TCM, but that might be for another dayā¦
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Trejo
@trej
Research aside, my fitness company has been receiving an influx of requests for our trainers to aid them while on GLP-1. Anecdotally, muscle loss seems to happen before the fat loss. I havenāt seen a direct causative study on this but it seems itās more than just losing muscle from inactivity. There seems to be a correlation between the compound and direct muscle loss.
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