Greg Robinson
@gregrob.eth
My wife and I were debating the use of supplements yesterday. We got on to NAD+ and 🤔: People with high X (cell health) have high Y (NAD+). If we measure Y to determine X, does supplementing Y raise X (cell health) or does it just increase Y (the thing we measure -> NAD+). Does anyone know? cc: @bryanjohnson
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Kieran Daniels 🎩
@kdaniels.eth
@askgina.eth what do you think about this?
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Alex Loukissas 🍉
@futureartist
According to Attia, evidence is lacking on NAD+ https://www.perplexity.ai/search/nad-peter-attia-8PFt8e6FRQS2OQBdKQxyWQ
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FrensFerdinand
@frensferdinand
Also supplementation doesn’t take into account things like bioavailability of something, the form it’s being consumed in, as we are finding out when adding a mineral to a food doesn’t necessarily mean you will absorb it the same way if you were consuming a food rich in the mineral
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s5eeo
@s5eeo
From observational data or observational studies alone, you cannot know whether an association between two things is because of a direct causal link between them or not. So then you wouldn’t know whether changing one variable would actually affect the other. That’s why it’s important to do randomized controlled trials, which is a form of active experimentation. With those, you can get evidence that suggests whether there is a direct causal link or not and whether changing one variable (e.g. taking a medication or supplement) would affect the other (e.g. longevity or improved health outcomes).
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🌹 zach harris 🥀
@zachharris.eth
These are one of the more reputable longevity supplements out there… the challenge with all of this stuff is there’s not enough clinical evidence to really fully confirm efficacy rates. https://www.perplexity.ai/search/how-does-elyssium-health-work-gn3C_nx.TiitRvg611N1ow
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Samu 🔆
@samu
all i can say is that personally when ive been using NAD+ (Tru Niagen brand) I have even higher performance and energy levels than my baseline Ran out last week and ordered a six month supply when it was on sale the other day Worth to keep it in the stack
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