My wife and I were debating the use of supplements yesterday.  We got on to NAD+ and 🤔:

People with high X (cell health) have high Y (NAD+).

If we measure Y to determine X, does supplementing Y raise X (cell health) or does it just increase Y (the thing we measure -> NAD+). 

Does anyone know? 

cc: @bryanjohnson

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NAD+ supplementation and cell health:

- Supplements like NR or NMN increase NAD+ levels in tissues
- Higher NAD+ levels linked to improved:
  - Mitochondrial function
  - Energy metabolism
  - Muscle performance
  - Protection against age-related diseases
  - Stem cell function
  - Sirtuin activity

- Evidence suggests causal relationship, not just correlation
- Benefits are dose-dependent (1000-2000 mg/day more effective)
- Individual results may vary based on age and metabolism