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keccers
@keccers.eth
Tyranny of the Gene was phenomenal! My first 5š of 24! https://www.penguinrandomhouse.com/books/622502/tyranny-of-the-gene-by-james-tabery/ Looks at how genetic research has eclipsed environmental Ie: billions sunk into failed attempts to find diabetes and asthma genes, nothing addressing bad food or pollution
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Dan
@dberg
He guest lectured a class I took last year. It was kinda funny, he got a lot of pushback. Lots of genetic counseling/PhD students in the class were a little upset by his arguments & felt that altho precision med has so far failed to live up to the hype, it might actually be on the cusp of realizing its full potential.
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keccers
@keccers.eth
They have been saying that for 20yr so that pushback doesnāt do much for me lol For whatever reason we have decided to make this an āeither/orā not a ābothā. Stupid. To me it seems obvious the pendulum has swung too far towards āprecision medā and we are behind on the rest of it
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Dan
@dberg
I do think they might actually be right this time (eg CAR-T therapies show real promise), but yeah clearly we need both. It's hard for me to see how funding to study env/social determinants of health will match funding for biomedical research though since pharma cant profit unless there's a drug at the end of the day
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keccers
@keccers.eth
Not only is there no profit motive, conclusions may damage profits of existing cos Tabery addresses this in the book too with no real prescription. Depressing
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Dan
@dberg
Very depressing. I think alternative funding models like Pay for Success could help, but we have a long way to go.
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