Can one be physically addicted to work?

During a recent 1-wk vacation to a wonderful, my body felt very "off" for a most of the time. Now back to intense working, I feel physically great. 

Has my body formed hormonal rhythms that are optimized around working intense, long hours? And upon deviations...withdrawals??

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Absolutely 
And sometimes your brain has adapted to a certain routine, so much that when you are absent from it, you feel like you’re going through a withdrawal 

It’s the same mechanism, basically.

Oh and it involves physical health, I’m definitely gonna have an opinion lol.

Do you get enough rest? Cus it seems like you work long hours alot