Can one be physically addicted to work?

During a recent 1-wk vacation to a wonderful, my body felt very "off" for a most of the time. Now back to intense working, I feel physically great. 

Has my body formed hormonal rhythms that are optimized around working intense, long hours? And upon deviations...withdrawals??

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spent lots of august traveling and had the same feeling, super off balance

first day in office in september, was locked in for 10 hours with deep concentration

instantly felt better

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Interesting! 🤔
(I am doing armchair neurobiology as we speak...)