notdevin on Warpcast

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Colin pfp

Anyone have experience with Nucleus DNA sequencing? https://mynucleus.com They claim it's substantially better than 23andMe and other competitors. I'm a sucker for that type of longevity data analysis

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christin pfp

curious what @keccers.eth and @serendipity think... I poked around and sure, whole genome gives you more data than chips, but if they are working off the same bank of public data off clinvar then the variant info would be similar they claim to "merge" BMI/age/sex and birth risk with the DNA data...(con't)

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...which makes me raise eyebrows a bit b/c it becomes a game of proprietary calculations where you can never really disprove their data unless they publish something that shows their calculations match actual study results they claim to filter data by ethnicity which technically 23andme already does (usually means...

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...not much data for people of non-european descent, sadly) overall, the issue with all genetic data <-> health startups is that the foundational data for polygenic diseases that everyone relies on are not very good quality b/c of the complexity involved, and monogenic highly penetrant diseases are relatively rare

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<I used to be a researcher who specialized in human genetics, so I saw the good/the bad/the ugly of this field!> their website design is pretty though...

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lastly, my personal opinion: even "bad" data, if it can motivate "good" behavior...may be worth it 🙂

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I think, especially for some of these variants where the link to disease is especially tenuous, it's worth examining as well what you will get out of the knowledge. Much of it simply is not actionable beyond what you might do anyways as a healthy person. Shadow of a "cursed bloodline" looms large

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notdevin pfp

I interpret any and all health sensor data as a reminder that if I shop the outside of the grocery store, stay hydrated, get sleep, and exercise, I’ll think, perform, and feel better

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"bUt It'S cOmPLicAtEd!!!" If this were true, nerds would be the most ripped & beautiful people on earth.

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Hahaha totally! The most technical details only become effectual at the most extreme end of the performance spectrum, otherwise the primary factors dominate the outcomes so much that there’s no point in making it your profession unless your profession depends on it and even then you may just be maxing out placebo

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The cheeky way to say this is “don’t major in the minors!”

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