Giuliano Giacaglia pfp
Giuliano Giacaglia
@giu
Anyone into longevity agrees/disagrees with Elon here. Why? https://i.imgur.com/bVcFC2h.jpg
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ted (not lasso) pfp
ted (not lasso)
@ted
from Nick Lane, imo the premier evolutionary epigeneticist: "Over six million years of evolution, since we split off from the apes, we have already extended our own maximum lifespan by five or six-fold, from 20 or 30 years to about 120 years... these changes were wrought by natural selection [ie genetic modification]"
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Shane Glynn pfp
Shane Glynn
@cno
If Elon’s argument was correct insurance companies wouldn’t ask if you smoke. :-) And twin studies show that BMI, smoking, alcoholism, and drug use are bigger factors than genetics in longevity. The famous Danish twin study showed the heritability of longevity to be ~0.25.
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Warren pfp
Warren
@warren
don’t bet against epigenetics!
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Varun Srinivasan pfp
Varun Srinivasan
@v
both statements are correct - its possible to live longer through exercise, medication, testing and treatment and you will not be able to start a life insurance company that capitalizes on that though the latter is true more for reasons of regulation, ethics and measurement challenges
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ted (not lasso) pfp
ted (not lasso)
@ted
i had no idea that we had so many geneticists and molecular biologists on farcaster until this cast 😜
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Pierrick pfp
Pierrick
@pierrick
Isn’t he proving the point of the guy with his reply? Health insurance will be higher if you smoke for example.
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danny iskandar pfp
danny iskandar
@daniskandar
my impression is either Elon is ignorant about longevity study or just talking pass each other. heard he is eating donut every morning, so it seems he does not believe in "Sinclair' science. If that is true, that is stupid and sad coming from him.
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Syed Shah🏴‍☠️🌊 pfp
Syed Shah🏴‍☠️🌊
@syed
I think it’s confusing individual level impact vs macro view. A few people start doing changes dramatically impact their life quality but it won’t show up in insurance numbers until people do it enmasse. To wait for data to show up at that level and to argue against impact until it shows up there is asinine at best
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mk pfp
mk
@mk
Mostly disagree. IMO Elon is using an over-simplified version of genes that doesn’t account for regulation. Squirrels live about 10x as long as rats with a similar set of genes. Clean living isn’t enough, but it doesn’t take too much tweaking to get a lot more time out of the same genes.
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notdevin pfp
notdevin
@notdevin.eth
Both are true. I believe the fastest cars have insane horsepower I believe the fastest cars have insane torque The truth is the fastest cars have a high number of each but if you take one away the car will be below average
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Robin A. pfp
Robin A.
@degenroot.eth
To some extent he is right due to genetic pre-depositions. However it is usually the environment around you and your lifestyle that triggers a genetic predisposition. *This should by no account me taken as a precise account, however in neuroscience, genetics account for 60-69% depending on a given developing disease
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tldr (tim reilly) pfp
tldr (tim reilly)
@tldr
I think he’s defining “genes” more on the species-level (rather than individual variation). And in this sense he’s right that if there were species-level insight into longevity there’s no way he/we could miss it. (Market forces would cause it to upturn the world like a tidal wave 🌊)
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CBobRobison pfp
CBobRobison
@cr
Interesting argument. Reminds me of "why do people buy real estate on the coast while believing climate change will devastate the coasts?" I've seen disease go into remission via epigenetics with staggering statistical significance, so I fundamentally disagree "it's in our genes." But I do think he has a point...
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ProfBiceps pfp
ProfBiceps
@profbiceps
Total disagree on this. I think it's best displayed in blue zones where you can see the server decay of life expectancy once they adopt western diet and lifestyle.
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mactar pfp
mactar
@mactar
Sinclair is the GOAT in the field as far as I’m concerned… reminds me of Elon promoting Doge
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borodutch @ lunchbreak.com pfp
borodutch @ lunchbreak.com
@farcasteradmin.eth
you don't have to disagree when facts are on your side it's elon who disagrees with facts this is the same mouse before and after the treatment https://i.imgur.com/7HVazkL.jpg
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Breck Yunits pfp
Breck Yunits
@breck
Agree with Elon. "Studies show" is a very weak phrase. Give me links to something showing *orders of magnitude* effects or it's probably B.S. That being said, I'm 1% open to the possibility there are vampires amongst us who have been alive for hundreds of years and do an excellent job of hiding the secret.
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Ryan Reef pfp
Ryan Reef
@ryanreef
Disagree with Elon. Elon is viewing the world through business which only captures a tiny fraction of reality.
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Snar pfp
Snar
@snar
Agreed, life insurance business is so big, id jump through one set of extra hoops to prove my longevity for a rate discount if it was offered. Any other extensive on going surveillance would severely cut into profit margins.
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