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Can one be physically addicted to work?

During a recent 1-wk vacation to a wonderful, my body felt very "off" for a most of the time. Now back to intense working, I feel physically great. 

Has my body formed hormonal rhythms that are optimized around working intense, long hours? And upon deviations...withdrawals??

building /bracket | talking /greatbooks | ex-BCG, ex-PHD | poli + phil + econ

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1450 $degen