Week 1 NFL picks, predictions, best bets from Vegas expert: This 3-team football parlay pays almost 6-1
The Week 1 NFL odds were released after the NFL schedule came out in May, but a majority of NFL bets roll in during the days leading up to the openers. While making NFL picks against the spread remains popular, Week 1 NFL parlay picks are also being assembled as bettors look for the opportunity to multiply their payouts. Key Week 1 NFL lines via the SportsLine Consensus include Chiefs (-3) vs. Ravens, Eagles (-2.5) vs. Packers, and Lions (-3.5) vs. Rams.

All those games will receive plenty of national attention and adjustments to the NFL betting lines during the Week 1 NFL schedule. However, savvy bettors are taking a close look at all 16 games as they look for the best values in the NFL spreads. Before you make any Week 1 NFL picks or NFL parlays, be sure to see what SportsLine senior analyst Larry Hartstein has to say.