My team and I are building Monadic DNA, the next generation of personal genomics. We’ll be using the latest in secure computation including MPC, FHE and ZK.

https://monadicdna.com/

Watch my feed as I think out loud and leave progress updates.

I am not working on a blockchain app but an app ecosystem which uses blockchains with a light touch. 

Here are the related and adjacent features I am aiming for in a next generation personal genomics product:

Building decentralized things since 2013.

https://cryptonomic.tech/

Coordination: Blockchains should be used for coordination between actors but not for computation or storage. The less smart contracts are used, the better. The dumber smart contracts are, the better.

Comedy of the commons: The utility of the app should grow with the numbers of providers and users on the platform without running into any technical hard limits or saturation or limits on the number of actors and participants.

Decentralization: The app should not rely on the existence or fitness of any one entity. Users should not be locked into any single interface or actor. My own organization should only stay in business as long as it is the best at what it does for the ecosystem.

Composition: Attestations are great for coordinating on an open ecosystem. Blockchain attestations, e.g. using Sign Protocol, should be used to build chains of trust and composing results and business processes between different providers.

User sovereignty: User should directly own their data and identity (with good UX). Their active consent should be needed for anything requiring their data. People should be able to modify and delete their own data at any instant they wish.

Infrastructure: Finally, the underlying storage and compute infrastructure itself should not be controlled by any single entity and blockchains should be used for coordination, especially payments for the infrastructure providers (e.g. @nillion).

Comedy of the commons: The utility of the app should grow with the numbers of providers and users on the platform without running into any technical hard limits or saturation or limits on the number of actors and participants. 

https://wiki.p2pfoundation.net/Comedy_of_the_Commons