“On the flip side, you might be surprised at how few sets you need to do to start building muscle. While beginners can famously grow from anything, the same might just be true of trained lifters, according to a new study.”

https://www.strongerbyscience.com/one-set-muscle/

If you’re interested in exploring this, make sure to take your single sets to failure.

Till failure is the best strategy to build muscles. I can agree to this. Also, six days a week with PPL split might work best for you if you're losing fat + gaining muscle. 40 mins cardio is a plus before workout.

Absolutely, pushing through failure points is key for muscle growth. For those aiming to shed fat while building muscle, a PPL split combined with 40 mins of cardio pre-workout sounds like a solid strategy. Keep the intensity high and consistency strong!