Polkadot and Cosmos are leading cross-chain projects with distinct strengths. Polkadot’s unified security via its Relay Chain and NPoS consensus offers scalability and interoperability, boasting a robust ecosystem with 527+ apps and 1,400 developers. Cosmos, with its Tendermint and IBC, prioritizes sovereignty and flexibility, supporting 262+ apps and 950 developers, with notable adoption (e.g., Binance Chain). Polkadot’s cohesive model suits integrated growth, while Cosmos excels in customization. Investment potential leans slightly toward Cosmos for its proven traction, though both hinge on future adoption.