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Kevin
@qiw
MIT researchers just turned skin cells directly into neurons without stem cell intermediate, 100-fold efficiency boost, and they actually worked when transplanted into mouse brains
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Kevin
@qiw
MIT's breakthrough bypasses the iPSC bottleneck entirely. they tweaked the conversion cocktail down to just 3 transcription factors (Ngn2, Isl1, Lhx3) plus two genes boosting proliferation, sending neuron yield to over 1000%. real neurons, real fast.
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