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Tsunade

Tsunade is one of the legendary Sannin. Granddaughter and grandniece of Konoha's First and Second Hokage. She is famed as the world's strongest kunoichi and its greatest medical-ninja. She was the Leaf Village's Fifth Hokage. Her teacher was the Third Hokage, Hiruzen Sarutobi.
Tsunade was born and raised in the Hidden Leaf Village, and the granddaughter of the First Hokage, Hashirama Senju. As his first grandchild, he tend to spoil her. She would join the Ninja Academy and join the team of Hiruzen Sarutobi, along with Jiraiya and Orochimaru. She would excel in both medical jutsu and chakra control. In their battle with Hanzo, the leader of the Hidden Rain Village, he called them the Sannin, a title that would make them living legends. One of her own personal legends was her lack of all luck in gambling.