longevity

What's the best tool for genome data analysis?

Co-Founder at sablier.com, and open-source developer. I have a broad range of interests, including longevity, epistemology, physics, and psychology.

Which provider you've used for whole-genome sequencing? 

Recently learned that some of them are actually non-clinical grade and data might be incorrect.

None of the consumer services are clinical grade.

Even specialized labs only working with hospitals have special plans for doing full CLIA validated sequencing.

E.g. https://www.genewiz.com/en-GB/Public/Services/Clinical-Services/CLIA-Whole-Genome-Sequencing

But they won't ever talk to a non medical client.

• depin in the sky /spacecoin 
• prime coxswain /koda
• network state /subwork • angel n' lp in few funds
• yangwao.twitter •

Why wont labs talk to non medical clients? Good question! My guess is that it's not worth it.

The seqeuncing is not a good business model. Finding leads only for one-shot interaction is low profit.

Charging more to cover clinical gradeness would just lose even thise few leads to others who yolo.

Annoyingly, hospitals providing genetic services will play into this (my guess through service agreements with the labs actually doing the seqeuncing).

Even if they charge you say 4000 EUR to do a sequencing, the hospital will refuse to give you the data; rather you can then book 100 EUR session to "talk" about it.

What they can charge for is interpretation. By having doctors as clients' they have a perpetual back and forth about one or more patients.


Or they value research and publications, but need data ownership for that. Usually the terms going through doctors will ensure they retain the data forever.