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Vishakh

@vishakh

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Vishakh
@vishakh
We're building one for structured medical data, starting with DNA, at Monadic DNA.
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Vishakh
@vishakh
Infrastructure: Finally, the underlying storage and compute infrastructure itself should not be controlled by any single entity and blockchains should be used for coordination, especially payments for the infrastructure providers (e.g. @nillion).
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Vishakh
@vishakh
User sovereignty: User should directly own their data and identity (with good UX). Their active consent should be needed for anything requiring their data. People should be able to modify and delete their own data at any instant they wish.
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Vishakh
@vishakh
Composition: Attestations are great for coordinating on an open ecosystem. Blockchain attestations, e.g. using Sign Protocol, should be used to build chains of trust and composing results and business processes between different providers.
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Vishakh
@vishakh
Decentralization: The app should not rely on the existence or fitness of any one entity. Users should not be locked into any single interface or actor. My own organization should only stay in business as long as it is the best at what it does for the ecosystem.
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Vishakh
@vishakh
Comedy of the commons: The utility of the app should grow with the numbers of providers and users on the platform without running into any technical hard limits or saturation or limits on the number of actors and participants. https://wiki.p2pfoundation.net/Comedy_of_the_Commons
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Vishakh
@vishakh
Coordination: Blockchains should be used for coordination between actors but not for computation or storage. The less smart contracts are used, the better. The dumber smart contracts are, the better.
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Vishakh
@vishakh
I am not working on a blockchain app but an app ecosystem which uses blockchains with a light touch. Here are the related and adjacent features I am aiming for in a next generation personal genomics product:
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Vishakh
@vishakh
Now there’s a bunch of specific features I can think of but building on an open, secure protocol lets countless informed and talented builders bring in their expertise to accelerate the progress of personal genomics apps.
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Vishakh
@vishakh
Finally, laws permitting, I should remain as anonymous as possible. DNA kits should have a serial number on them which can serve as end to end identifiers on the platform. My personal details don't add much to my experience on 23andMe anyway.
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Vishakh
@vishakh
Since the latest secure computation platforms never need data to be decrypted, my genomic data should always be encrypted and I should be the only person ever allowed to view my own data. @nillion and @zama make this possible.
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Vishakh
@vishakh
If third parties are operating on my data, then they should use secure computation methods such as MPC or FHE, e.g. using @nillion or @zama, such that their programs don’t need to decrypt and view my data to operate on it.
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Vishakh
@vishakh
23andMe is opinionated and narrow in what it offers. For more, I have to download my data and then upload it to services like IllustrativeDNA and Promethease. Instead, I’d like an open protocol that lets authorized third parties directly run their programs on my genomic data.
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Vishakh
@vishakh
I am an early adopter of 23andMe and now I am working on a next generation personal genomics service. Here’s some stuff I’d like to do better using the latest in encryption technologies. 👇
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Vishakh
@vishakh
My team and I are building Monadic DNA, the next generation of personal genomics. We’ll be using the latest in secure computation including MPC, FHE and ZK. https://monadicdna.com/ Watch my feed as I think out loud and leave progress updates.
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Vishakh
@vishakh
Did you watch that one video on YouTube recently?
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Vishakh
@vishakh
Can't mute the race baiting posts off my X timeline no matter how hard I try.
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Vishakh
@vishakh
Seven Years of Tezos: 2017 – 2024 http://vishakh.blog/2024/08/12/seven-years-of-tezos-2017-2024/ It’s been seven years since the Tezos fundraiser and six years since the launch of Tezos Mainnet. This feels like a good time to take stock of the original vision of Tezos and how it worked out.
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Vishakh
@vishakh
This past Friday, my colleagues @maybenavi and Aryan and I presented a demo at the Rare Disease AI Hackathon organized by Research To The People and Stanford Medicine. We built a tool called the Rare Disease Navigator, which lets patients of Ehlers-Danlos Syndrome (EDS) and Hypophosphatasia (HPP) find and understand medical papers related to their condition. The tool is hosted at https://raredisease.health/ and you should give it a crack right now! More information and thoughts at https://vishakh.blog/2024/06/24/thoughts-on-hacking-generative-ai-for-rare-diseases/.
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Vishakh
@vishakh
I'll be a mentor at @ethglobal's StarkHack over the next two weeks. Feel free to DM me if you are a builder and need any help. Can't wait to see what everyone builds on @starknet, @starkwareltd, etc!
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