Sean Brennan

@seanwbren

2494 Following

7825 Followers

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Just minted Day 496 on BasePaint -- Ugly Based Christmas Sweater Hundreds of pixel artists made this together on the blockchain. Minting is open for 5 more hours.

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https://warpcast.com/chainleft/pack/Onchain-Artists-ilpowl

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thanks for the email notice @warpcast on 7.5k! For any new followers, I'm a dev/founder in the AI agent space, and have been building multiple projects for the last 2+ years after starting in the crypto space at Makerdao in 2017. Now in 2025, my focus is on applying agents to useful work in the automation and advancement of science. commonly called DeSci I've been building in the onchain AI space for nearly 2 years now, if you want to read my thoughts from Feb '23 it has some ideas for things starting to happen now. https://mirror.xyz/agentprotocol.eth/AbIhJJbKS0ZRxgtPCyKAUDX48wTTIuUi4r59ovym3z4 The project "Relay Robot" and "AgentProtocol.eth" were last-minute pivots from my DAO-Ops company called Daopanel, but it turns out I just needed the agents to launch memecoins and shill them lol. I believe the agents can do so much more than fill up your social feeds with memecoins, so follow along the @chainagent journey with me.

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if you appreciate @base art, today I made an alt account on X to curate the NFT collections I recommend and bag-hold. https://x.com/blue_0052fe

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de[centralized] gen[erative] _______ = /degendao could be the shift in 2025

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degendao clanks.

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try this out: https://onchain-agent-demo.replit.app/ https://x.com/OnchainKit/status/1856776390416502987

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at OpenAGI Summit at Devcon, this is a slide from a presentation by Google Cloud on their AI + Web3 approach

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I've been collecting @base art & NFTs for a year now - @gallery link in my bio. A recent launch I want to call out out is the Museum of Based Art by @joe-pxlr that is a meeting point and catalyst for the appreciation of based art and vibes. There is a long-term plan for art curation and collabs in the Museum, through bidding with the @zora erc1155 token Enjoyables: https://zora.co/collect/base:0x1426365a3a14a158c4fa2d4f02a56c5df36e3081/2 The current (thin) floor is at .022 for a small collection of 599 Portraits. Check it out: https://opensea.io/collection/moba--1?tab=items

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the best paper written so far about the impact of AI on scientific discovery

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A new team of agents python library from Microsoft https://t.co/iRhBXvNt69

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AI agents are maturing at coincidentally the exact same time that Base/@CoinbaseDev MPC wallets are coming online.

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@ensdomains first FrENSday conference at Devcon7 in Bangkok

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Llama 3.2 Vision is now in Ollama! Open source detailed image recognition. https://ollama.com/blog/llama3.2-vision reviews are that it is comparable (slightly inferior) to GPT4-Vision

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feels like we're living the Roaring 20's

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Devcon AI events not to miss: - OpenAGI Summit by Sentient https://lu.ma/7s7231aw - Agents Unleashed by Olas https://lu.ma/tdjehba6 - Coinbase AI Agents https://lu.ma/xcaeintf - Superintelligence Summit https://lu.ma/SuperintelligenceSummit - dAGI Summit: https://lu.ma/dagisummit

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where eth txs originate from and flow in their lifecycle before being confirmed in a block source: @archetype port co Essential talk on Intents: https://www.youtube.com/watch?v=la84UKBz-VE

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this was a crazy time in the feb/march degen bubble. The @partydao HIGHER club with 459 votes has a warchest of 240k USD of $higher

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Here is my Top 9 on @rodeodotclub featuring @segall 🍻🍻, @anirudhp, @antonis-tsagari, @praystation, @kongonongo, @chronist, and others

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on the topic of relying on AIs for critical infrastructure, and how to safely update/improve/adapt them to changing goals

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