Can one be physically addicted to work?

During a recent 1-wk vacation to a wonderful, my body felt very "off" for a most of the time. Now back to intense working, I feel physically great. 

Has my body formed hormonal rhythms that are optimized around working intense, long hours? And upon deviations...withdrawals??

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I've struggled going on vacations in the past couple years. Find it very hard to disconnect -- and not because anyone is making me stay online, I just like it here lol. But also --I've wondered what impact the dopamine hits have.