Can one be physically addicted to work?

During a recent 1-wk vacation to a wonderful, my body felt very "off" for a most of the time. Now back to intense working, I feel physically great. 

Has my body formed hormonal rhythms that are optimized around working intense, long hours? And upon deviations...withdrawals??

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I was thinking a similar thing about relaxation, and the idea that relaxation is not about having nothing to do, but doing things at a pace you enjoy or are used to

Be specific.     

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I had a similar but different thought with a friend a few months ago

— we want to do cool stuff
— we should really go something that also gets us a lot of money
— then we would have the autonomy to do whatever we want
— and then we could do loads of cool stuff

Wait why don’t we just do cool stuff now!

Dan shared something I found very useful recently, the distinction between people who Work To Live and Live To Work

Interesting thought! I had not considered what true relaxation is, but agree with you that “nothing” is a misleading answer that may be common. 

When I was in grade school, the only time I felt semi-existentially sad was when I had this thought that: 

“If I do all my work extremely well for many years — get a great job and make a lot of money — then I earn the ability to do… what? nothing? But that’s extremely boring.”

(Aristotle says that human happiness itself is being-at-work in virtue. This is really a profound concept when you start to look into it.)