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Iām not aware of any. But given how thick and relatively impermeable the skin of the feet is (or at least the soles), Iām dubious whether feet would be a significant route for either allergen sensitization or desensitization. As opposed to, say, exposure to soft, thin skin, or via inhalation or ingestion. Iād also want to consider overall risks/benefits. For example, even if shoes-off does reduce lifetime allergy risk, how does that weigh against increased risk of environmental injury (mechanical, chemical, thermal, etc) or greater risk of infection with soil-borne bacteria, fungi, or parasites? 0 reply
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