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Paul Berg
@prberg
Is any pharma company working on an eugeroic with a shorter half-life than modafinil? e.g. 6 hours instead of 12
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Leith Lyf
@leithlyf
as someone with narcolepsy who has done multiple clinical trials: unlikely to come to market via FDA approval and trials unless the military has a specific use case OR massive influx in developing better supports for nightshift workers. Because of the cost of trials, it's usually weighed against potential profit. There have been meds I was really looking forward to trying that didn't make it to market. And then sometimes aren't available in various countries: armodafanil wasn't brought to market in Canada for the longest time; zopiclone (sleeping pill, similar to zolpidem / Ambien, but different feel) generally doesn't seem to be available in the USA. And that generally the goal is developing longer acting, rather than shorter duration. But I can absolutely understand the "okay, brain has had enough focused alertness, can we just have this taper off until I want that level of functioning again"
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