We tend to think of genetic testing as infallible; convince ourselves that genes are destiny. But we’re so far from true mastery over the body that this simply isn’t the case 

What a blessing he has offered himself up to study; so that others can be helped 

https://www.npr.org/2025/02/12/nx-s1-5293253/his-genes-forecast-alzheimers-his-brain-had-other-plans

The Farcaster formerly known as Kchamp. Books, beats, bodybuilding, bright ideas and beautiful things.

katherinechampagne.com

This was my big gripe with the 23andme hype back in the day - genes are rarely a 1:1 genotype to phenotype 


 there is still so much we need to learn about epigenetics among other things...

microbiology PhD | fiber artist | synbio | scicomm | really into extremophiles

Would be so cool to prove that out. His cells could be (a less controversial) hela cell for researchers 

I recognize most of these things are nuanced and probably a combination of factors but in other organisms temperature can definitely  be a transcriptional regulator directly or indirectly

It’s fascinating, to your point about epigenetics one theory about this alz guy in the story is that because he spent huge portion of his life in like, Navy boiler rooms sweating his butt off in a super hot environment —- that consistent exposure to heat might have affected the way the gene expresses in him and  be saving him today